Unique technology and patent portfolio
SenesTech believes its technology is the first of its kind in the world. We have developed and patented species-specific protocols for animal population control by targeting the ability to reproduce.
For example, the active ingredients in our formulations chemically accelerate the depletion of eggs in female rats and cause testicular disruption in male rats. After ingesting the prescribed dose of our treatment, rats become infertile. The protocol has been refined and optimized to achieve follicle depletion and testis disruption without causing systemic toxicity or adverse side effects. Studies indicate that when used as directed the formulation is environmentally neutral, and will not affect the food chain.
No effect on non-target species
In laboratory studies, it has been shown that rats rapidly metabolize our active ingredients to inactive forms. Additionally, the half-life of our active ingredients in our product in the blood is less than 15 minutes in rodents. This data confirms that non-target species that consume rodents that have eaten our product will have no secondary effects.
No effect on humans
At the concentrations of active ingredients in our product there is no potential for reproductive disruption in humans. Further, the man-made chemical that is one of our active ingredients, has been used for decades in manufacturing settings with no reported toxic effects to humans. The other active ingredient is a plant-derived ingredient used for millennia in traditional Chinese medicine to treat symptoms of rheumatoid arthritis, and, is in current clinical trials in the U.S. to treat polycystic kidney disease, prostate cancer, bone cancer and pancreatic cancer.
The man-made active ingredient is rapidly broken down in water so there is no accumulation risk. The plant-derived ingredient is in our product at an extremely low concentration so it poses no accumulation risk.
We are conducting cutting-edge research in mammalian female and male senescence and developing animal research models, advancing efforts in wildlife population management.